Table of Contents
Hormones Genetic SNPs Table
Hormone SNPs provide information on the maintenance and metabolism of estrogen and testosterone, while also identifying the efficiency of thyroid function and circulating vitamin D levels. This data can also reveal insights into a person's melatonin release for glycemic control and how their gut health assists in the detoxification of hormone metabolites.
The following table is a collection of common genetic SNPs by the hormones health categories. These SNPs may be matched up with Standard Process and MediHerb Supplements that can provide support, when applicable.* Also, there may be one or more links to the research if you would like to dive deeper, when applicable.
To get an overview and learn more about Genetic SNPs, click here.
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| Genetic SNPs - HORMONES | Gene Name | Standard Process Products | MediHerb Products | Research |
|---|---|---|---|---|
| Sex Hormone Binding Globulin - If you are female, this genotype is associated with helping maintain normal estrogen and testosterone levels. Other epigenetic factors like obesity, fatty liver, and Type 2 diabetes should be considered when assessing SHBG levels. Testosterone-Men - If you are male, this genotype is associated with improved total and free testosterone levels for the SHBG rs6258 gene. | Sex Hormone Binding Globulin | E-Z Mg Zinc Chelate Livaplex Cruciferous Complete |
Adrenal Complex Damiana Liquid Vitanox |
1. HMG Article |
| Thyroid-DI01 - This genotype is associated with DI01 gene function for T3 and T4 thyroid function, however other epigenetic factors should be assessed. | Thytrophin PMG Trace Minerals B12 Cataplex E |
Thyroid Complex Rhodiola & Schisandra |
2. PRHR Article | |
| Thyroid-DI02 - This genotype is associated with T3 and T4 thyroid function in the brain for the DI02 gene. | Thytrophin PMG Trace Minerals B12 Cataplex E |
Thyroid Complex Rhodiola & Schisandra |
3. PRHR Article | |
| Estrogen Metabolism-CYP1A1 - This genotype is assoicated with the beginning phase of estrogen metabolism. Please review all genes involved in estrogen metabolism for a complete picture of the process. | cytochrome P450 1A1 | Cruciferous Complete Livaplex |
LivCo Rhodiola & Schisandra |
4. PubMed Article 5. GL Article 6. NCBI Article |
| Estrogen Metabolism-CYP2C19 - Individuals with the TT genotype for CYP2C19*17 are considered the ultra-rapid metabolizer phenotype. This may positively add to the cumulative value for improving estrogen metabolism. Please review all genes involved in estrogen metabolism for a complete picture of the process. | cytochrome P450 2C19 | Cruciferous Complete Livaplex |
LivCo Rhodiola & Schisandra |
7. PubMed Article 8. Res Gate Article |
| Estrogen Metabolism-CYP1A2 - For men and women with the CYP1A2 AA genotype, coffee intake was found to be more protective against estrogen receptor-positive breast cancer and prostate cancer. | cytochrome P450 1A2 | Cataplex B Core Betafood Cruciferous Complete Livaplex |
LivCo Rhodiola & Schisandra |
9. PubMed Article |
| Estrobolome-FUT2 - This genotype is associated with bifidobacteria gut bacteria, assisting the gut phase of estrogen detoxification. | fucosyltransferase 2 | GI Stability Lactic Acid Yeast Spanish Black Radish Livaplex |
Berberine Active LivCo |
10. PubMed Article 11. PubMed Article |
| Vitamin D-CYP2R1 - This genotype is associated with circulating vitamin D levels that can affect immunity, breast health in women, and testosterone levels in men. Check your vitamin D levels and make sure you are in range. *Consume 1000 IU (25 mcg) vitamin D daily. | cytochrome P450 2R1 | Cataplex D Cod Liver Oil Chlorophyll Complex |
LivCo | 12. PubMed Article |
| Estrogen Metabolism-COMT - For estrogen metabolism and detoxification, those with the intermediate AG COMT V158M genotype may have an increase in harmful estrogen metabolites that can cause DNA damage. To reduce the risk of these metabolites, you should avoid xenoestrogens, manage stress levels, maintain gut health, increase magnesium intake, and consume green tea polyphenols. | catechol-O-methyltransferase | Cruciferous Complete Livaplex |
LivCo Rhodiola & Schisandra |
13. Nature Article 14. PubMed Article 15. MGF Article |
| MTNR1B-Melatonin - This genotype is associated with melatonin release, a longer duration of morning melatonin levels, and less insulin release during late night and early morning feeding could occur. It is recommended to eat dinner early, avoid late night snacking and consume breakfast later in the morning for better glycemic control. | melatonin receptor 1B gene | Protefood B6 Niacinamide Cataplex B2 |
Chaste Tree | 16. NCBI Article 17. PubMed Article 18. NCBI Article |
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If you have specific concerns or a situation arises in which you require medical advice, you should consult with an appropriately trained and qualified medical service provider. This content is intended for informational purposes only and is not intended to replace or substitute for any medical or other advice.